APOLLO
APOLLO
[MELC 22] Recognize the major categories of biomolecules such as carbohydrates, lipids, proteins, and nucleic acids. (S10MT-IVc-d-22)
Day 1: Describe carbohydrates and their classification (monosaccharide, disaccharide, and polysaccharide).
Day 2: Describe lipids and differentiate the two classes of lipids (simple and complex).
Day 3: Discuss the structure, uses, and function of nucleic acids
Day 4: Discuss the structure, uses, and function of proteins.
This biomolecules are often shortened to carbs, which serve as the body's primary source of energy. They are made up of carbon, hydrogen, and oxygen atoms, with a general formula of Cx(H2O)y. Their structure can range from simple sugars to complex sugars as shown in the diagrams below.
Types of Carbohydrates
Carbohydrates are classified into two main types based on their chemical structure and complexity:
Simple carbohydrates are small, single sugar molecules or short chains of sugars that are quickly absorbed by the body and cause a rapid rise in blood sugar levels. Simple carbohydrates can be categorized based on their chemical structures, monosaccharides and disaccharides. Monosaccharides are single sugar molecules, while disaccharides consist of two single sugar molecules joined together.
Glucose: Primary energy source, found in fruits, vegetables, and honey.
Fructose: Naturally occurring in fruits, vegetables, and honey; the sweetest natural sugar.
Galactose: Found in milk and dairy products, usually as part of lactose.
Sucrose: Composed of glucose and fructose, commonly known as table sugar, found in sugar cane, sugar beets, and many fruits and vegetables.
Lactose: Made of glucose and galactose, the main sugar in milk and dairy products.
Maltose: Consists of two glucose molecules, found in malted foods, beverages, and some grains.
Complex carbohydrates also referred to as polysaccharides, are larger, more complex molecules made up of long chains of sugar units. They take longer for the body to break down and release glucose, resulting in a more gradual and sustained rise in blood sugar levels.
Examples include:
Starches (found in grains, potatoes, and corn)
Fibers (found in fruits, vegetables, and whole grains)
are fatty compounds essential for various bodily functions. They regulate the movement of substances in and out of your cells by forming part of your cell membranes. Additionally, lipids are involved in energy storage and transport, vitamin absorption, and hormone production [©].
Types of Lipids
Simple lipids are esters of fatty acids with various alcohols and include triglycerides, which are composed of three fatty acid molecules attached to a glycerol backbone, serving as the primary form of stored energy in animals and plants, found in fats and oils. Waxes, another type of simple lipid, are esters of long-chain fatty acids with long-chain alcohols that provide protective coatings on plant leaves, fruits, and animal fur or feathers.
Complex lipids contain additional groups such as phosphates, carbohydrates, or proteins. Phospholipids, composed of two fatty acids, a glycerol backbone, and a phosphate group, are major components of cell membranes. Glycolipids, which have a carbohydrate attached, are important for cell recognition and interaction and are found in cell membranes, particularly in the brain and nervous tissue. Lipoproteins are complexes of lipids and proteins that transport lipids through the bloodstream, with types including low-density lipoproteins (LDL) and high-density lipoproteins (HDL), commonly referred to as "bad" and "good" cholesterol, respectively.
were discovered in 1869 by Swiss biochemist Friedrich Miescher. Nucleic acids are long chainlike molecules composed of a series of nearly identical building blocks called nucleotides. Each nucleotide consists of a nitrogen-containing aromatic base attached to a pentose (five-carbon) sugar, which is in turn attached to a phosphate group. They are naturally occurring chemical compound that are capable of being broken down to yield phosphoric acid, sugars, and a mixture of organic bases (purines and pyrimidines). They are responsible for coding genetic traits by controlling the production of proteins.
There are two types of nucleotides: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Deoxyribonucleic acid stores genetic information and directs the development of living organisms. It is the master blueprint for life and constitutes the genetic material in all free- living organisms and most viruses. Ribonucleic acid, on the other hand, transfers the genetic information stored in the DNA and directs the synthesis of proteins.
Nitrogenous Bases
Each nucleic acid contains four of five possible nitrogen-containing bases: adenine (A), guanine (G), cytosine (C), thymine (T), and uracil (U). Deoxyribonucleic acid contains Adenine (C10H12O5N5P), Thymine (C10H13O7N2P), Guanine (C10H12O6N5P) and Cytosine (C9H12O6N3P). Ribonucleic acid also contains the same nucleotide bases [Adenine (C10H12O6N5P), Guanine (C10H12O7N5P) and Cytosine (C9H12O7N3P)] except for Uracil (C9H11O8N2P). A and G are categorized as purines, and C, T, and U are called pyrimidines. All nucleic acids contain the bases A, C, and G; T, however, is found only in DNA, while U is found in RNA.
are large biomolecules and macromolecules that comprise one or more long chains of amino acid. Essential for proper bodily function, proteins serve as the building blocks of structural components like skin and hair. Additionally, they play pivotal roles in the formation of enzymes, cytokines, and antibodies, among other vital substances.
Types of Amino acids
9 Essential (Histidine (C6H9N3O2), Isoleucine (C6H13NO2), Leucine (C6H13NO2), Lysine (C6H14N2O2), Methionine (C5H11NO2S), Phenylalanine (C9H11NO2), Threonine (C4H9NO3), Tryptophan (C11H12N2O2), and Valine (C5H11NO2)
11 Nonessential amino acids (Glycine (C2H5NO2), Alanine (C3H7NO2), Proline (C5H9NO2), Serine (C3H7NO3), Tyrosine (C9H11NO3), Aspartic Acid (C4H7NO4), Glutamic Acid (C5H9NO4), Asparagine (C4H8N2O3), Glutamine (C5H10N2O3), Arginine (C6H14N4O2), and Cysteine (C3H7NO2S).
Protein Structure
Proteins are constructed through the condensation of amino acids, which form peptide bonds. The primary structure of a protein refers to the specific sequence of amino acids along its chain. Secondary structure arises from the angles of these peptide bonds, while tertiary structure results from the spatial folding of protein chains. Complex functional proteins can further assemble from multiple folded polypeptide molecules, forming their quaternary structure [©].
Functions of Proteins
Enzymes: Catalysts that facilitate biochemical reactions.
Structural Components: Provide support and strength to cells, tissues, and organs.
Transport: Carry molecules (e.g., oxygen in hemoglobin) throughout the body.
Hormones: Act as chemical messengers that regulate various physiological processes.
Immune Function: Antibodies defend against pathogens and foreign substances.
Movement: Contractile proteins enable muscle movement.
Regulation: Control gene expression and other cellular activities.